Mostly, FSGS presents as a Nephrotic Syndrome. According to statistics, about two-thirds of patients have heavy proteinuria and serious swelling, and the urine protein usually is about 1-30g/d. Nearly 50% patients show hematuresis and in general, microscopic hematuresis is more common. About 30-50% patients have light degree of hypertension (high blood pressure) or presented as chronic nephritis syndrome.

Some patients have no obvious symptoms, and proteinuria is occasionally found during urine routine. And this kind of asymptomatic proteinuria could last for a long time and prognosis for this type is good. Some minority patients may gradually progress into end stage renal failure. Children sufferers have a similar clinical symptoms with adults. And they are mainly presented with Nephrotic Syndrome. The morbidity rate for high blood pressure and renal insufficiency in children is lower than in adults. Most of FSGS(40-60%) progress with presentations of chronic feature and it may progress to kidney failure at last. Some minority patients(10-15%) progress quickly so patients could show renal failure at an early time.

All in all, the early treatment you can take, the better prognosis you will get.

Topic: FSGS Basics