Chronic Kidney Disease(CKD) is divided into five stages based on your glomerular filtration rate (GFR) and the presence of the kidney damage. Stage 4 CKD comes with severe kidney damage. There are many cases that can increase the risk of stage 4 CKD. Can high blood pressure and diabetes increase the risk of stage 4 CKD?

Can high blood pressure increase the risk of stage 4 CKD?

High blood pressure is a leading cause of CKD. Patients with high blood pressure is at a high risk of developing CKD. How high blood pressure affect kidney?

High blood pressure will cause damage to the blood vessels in the whole body. Thus the blood volume that pass through the kidney will be decreased, causing hypoxic-ischemic to the kidney.

High blood pressure also can damage glomerular, which is the main filtration unit of kidney. Thus kidney cannot well filtrate the waste and toxins and extra fluid in blood. The buildup of these product in blood will increase high blood pressure in return.

So if you are attacked by high blood pressure, it will worsen the kidney disease. High blood pressure can increase the risk of stage 4 CKD. If you have developed into stage 4 CKD, you are suggested to well control the blood pressure.

Can diabetes increase the risk of stage 4 CKD?

Diabetes is also a leading cause of CKD. How diabetes affect kidney?

When the body cannot produce enough insulin or cannot make use of the insulin, diabetes will occur. Insulin is a kind of hormone that controls sugar amount in the blood. The blood sugar level will be increased with diabetes.

High blood sugar can narrow the blood vessel as well as clog the blood vessel. This can cause the decrease of the blood through kidney and cause microcirculation disorder. This will further increase the damage to the surrounding capillaries and the infiltration of the inflammatory cells. A great amount of extracellular matrix will form and replace the healthy kidney inherent cells.

So diabetes will increase the risk of developing CKD and it can also worsen the illness condition. So diabetes can increase the risk of stage 4 CKD.

From the above we can see that high blood pressure and diabetes can increase the risk of stage 4 CKD. You are suggested to control high blood pressure and diabetes to prevent the deterioration of the kidney disease. You can consult the online doctor if you have problems.