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Amyloidosis is a rare systemic disease in which an abnormal protein amyloid builds up in your tissues and organs. The most commonly affected body parts are the kidney, heart, liver and so on. when your kidneys are involved, what will happen?
Actually, renal amyloidosis include primary amyloidosis, secondary amyloidosis, family or hereditary amyloidosis and dialysis-related amyloidosis.
Primary amyloidosis
It occurs when the body’s antibody-producing cells do not function properly and produce abnormal protein fibers made antibody fragments. Some people with primary amyloidosis have a condition called multiple myeloma. Injured kidneys can’t function effectively and may be unable to remove urea and other wastes from the blood. Elevated levels of these protein fibers can also damage the heart, lungs, brain, and digestive system. And proteinuria is the most common symptom of this disease.
Secondary amyloidosis
This is result of chronic inflammatory disease, such as lupus, rheumatoid arthritis and so on. Patients may suffer from liver insufficiency, ascites, adrenal cortex edema and so on.
Family amyloidosis
This is a rare form that is passed down through families.
Dialysis-related amyloidosis
This is more common in older adults and people who have been on dialysis for more than five years. This form of amyloidosis is caused by deposits of beta-2 microglobulin that build up in the blood. It affects bones, joints and tendons.
As a matter of fact, men get amyloidosis more often than women, and the risk for amyloidosis increases as you grow older. The most commonly seen is that the primary and dialysis-related amyloidosis. It may occur in people with end stage kidney disease who are on dialysis for a long time.
Renal amyloidosis is a serious health problem that can lead to life-threatening organ failure. And the prognosis is poor compared to other kinds of kidney disease. More detailed info, please contact our online doctors or leave a message below and we will try our best to help you!
Amyloidosis is a rare systemic disease in which an abnormal protein amyloid builds up in your tissues and organs. The most commonly affected body parts are the kidney, heart, liver and so on. when your kidneys are involved, what will happen?
Actually, renal amyloidosis include primary amyloidosis, secondary amyloidosis, family or hereditary amyloidosis and dialysis-related amyloidosis.
Primary amyloidosis
It occurs when the body’s antibody-producing cells do not function properly and produce abnormal protein fibers made antibody fragments. Some people with primary amyloidosis have a condition called multiple myeloma. Injured kidneys can’t function effectively and may be unable to remove urea and other wastes from the blood. Elevated levels of these protein fibers can also damage the heart, lungs, brain, and digestive system. And proteinuria is the most common symptom of this disease.
Secondary amyloidosis
This is result of chronic inflammatory disease, such as lupus, rheumatoid arthritis and so on. Patients may suffer from liver insufficiency, ascites, adrenal cortex edema and so on.
Family amyloidosis
This is a rare form that is passed down through families.
Dialysis-related amyloidosis
This is more common in older adults and people who have been on dialysis for more than five years. This form of amyloidosis is caused by deposits of beta-2 microglobulin that build up in the blood. It affects bones, joints and tendons.
As a matter of fact, men get amyloidosis more often than women, and the risk for amyloidosis increases as you grow older. The most commonly seen is that the primary and dialysis-related amyloidosis. It may occur in people with end stage kidney disease who are on dialysis for a long time.
Renal amyloidosis is a serious health problem that can lead to life-threatening organ failure. And the prognosis is poor compared to other kinds of kidney disease. More detailed info, please contact our online doctors or leave a message below and we will try our best to help you!